Endoscopic Polypectomy: Surgical Removal of Polyps
Endoscopic polypectomy: removal of polyps during colonoscopy without surgery
Endoscopic polypectomy is the procedure that makes colonoscopy the only screening tool that prevents colorectal cancer—removing the polyp before it becomes malignant, without a single incision
Colorectal cancer takes 10–15 years to develop from a benign adenomatous polyp. That time is exactly the window colonoscopy has to act: detect the polyp in its benign phase and remove it during the same procedure—before it has the chance to become cancer. Endoscopic polypectomy is the reason colonoscopy reduces colorectal cancer mortality.
1. Types of colon polyps and their risk
| Polyp type | Histology | Risk of malignancy | Management |
|---|---|---|---|
| Hyperplastic polyp | Hyperplastic (non-neoplastic) | Almost zero—small recto-sigmoid hyperplastic polyps are minimum risk | Remove to confirm histology. Does not change the surveillance interval. |
| Tubular adenoma | Neoplastic—the most common (80%) | Low if <1 cm without high-grade dysplasia · Moderate if >1 cm | Always remove · Surveillance colonoscopy at 3–5 years |
| Villous / tubulovillous adenoma | Neoplastic—larger villous component | Higher than tubular · Pure villous reaches 40% malignancy if >2 cm | Always remove · More frequent surveillance |
| Adenoma with high-grade dysplasia | Neoplastic—close to carcinoma in situ | Very high—at the border with intramucosal cancer | Remove with confirmed clear margins · EMR or ESD if flat |
| Sessile serrated lesion (SSL) | Serrated—distinct epigenetics from conventional adenoma | Moderate-high especially if >1 cm with dysplasia | Remove en bloc · Surveillance at 1–3 years |
2. Polypectomy techniques—which one is used depending on the polyp
3. ESD—Endoscopic Submucosal Dissection—the advanced technique
Related articles
Sources
- ESGE. Guideline: Endoscopic management of colorectal polyps. esge.com. 2023. Cold snare, EMR, ESD. ESGE 2023
- USMSTF. Colorectal Cancer Screening Guidelines. 2024. Post-polypectomy intervals. USMSTF 2024
- van Doorn SC et al. Cold snare polypectomy vs hot snare. Endoscopy. 2024. van Doorn 2024

